Best Weight Loss Injections of 2026
Medically Reviewed by
Jessica Steele, MD
Ro
- ✓Multiple medication options including branded GLP-1s
- ✓Insurance eligibility checker built into onboarding
- ✓Body Program combines GLP-1s with metabolic health coaching
Why Ro Is Our #1 Pick
- ✓Multiple medication options including branded GLP-1s
- ✓Insurance eligibility checker built into onboarding
- ✓Body Program combines GLP-1s with metabolic health coaching
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
MEDVi
- ✓GLP-1 injections prescribed and shipped direct to your door
- ✓Compounded semaglutide and tirzepatide available
- ✓Licensed physicians manage your treatment plan
MEDVi
- ✓GLP-1 injections prescribed and shipped direct to your door
- ✓Compounded semaglutide and tirzepatide available
- ✓Licensed physicians manage your treatment plan
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Spring Deal: Your first month only $149 + free shipping
FuturHealth
- ✓Branded Wegovy access through licensed providers
- ✓Insurance support to help offset medication costs
- ✓Compounded semaglutide also available alongside branded options
FuturHealth
- ✓Branded Wegovy access through licensed providers
- ✓Insurance support to help offset medication costs
- ✓Compounded semaglutide also available alongside branded options
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Get started at $149 — no long-term commitment
TrimRX
- ✓Personalized GLP-1 weight management plans
- ✓Licensed physicians tailor treatment to your health profile
- ✓Fast medication shipping — often within days of approval
TrimRX
- ✓Personalized GLP-1 weight management plans
- ✓Licensed physicians tailor treatment to your health profile
- ✓Fast medication shipping — often within days of approval
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
New patient special: $179 all-inclusive first month
Yucca
- ✓Comprehensive weight management programs with medical supervision
- ✓Licensed providers create individualized treatment plans
- ✓Ongoing clinical support throughout your program
Yucca
- ✓Comprehensive weight management programs with medical supervision
- ✓Licensed providers create individualized treatment plans
- ✓Ongoing clinical support throughout your program
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Try it risk-free — $149 your first month
Eden
- ✓GLP-1 weight management treatments prescribed online
- ✓Board-certified providers evaluate your health profile
- ✓Discreet delivery directly to your door
Eden
- ✓GLP-1 weight management treatments prescribed online
- ✓Board-certified providers evaluate your health profile
- ✓Discreet delivery directly to your door
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Launch offer: $169 first month with coaching included
Jrnys
- ✓Weight management journeys combining coaching and medication
- ✓Personalized approach tailored to your lifestyle and goals
- ✓Licensed providers prescribe GLP-1 medications when appropriate
Jrnys
- ✓Weight management journeys combining coaching and medication
- ✓Personalized approach tailored to your lifestyle and goals
- ✓Licensed providers prescribe GLP-1 medications when appropriate
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Premium care from $159 — dedicated team included
IVY-RX
- ✓Premium telehealth experience with dedicated care team
- ✓GLP-1 prescriptions managed by experienced providers
- ✓Dedicated care team for personalized patient support
IVY-RX
- ✓Premium telehealth experience with dedicated care team
- ✓GLP-1 prescriptions managed by experienced providers
- ✓Dedicated care team for personalized patient support
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
No surprises: $149 flat — approved in 24 hours
Direct Meds
- ✓GLP-1 medications with transparent, upfront pricing
- ✓Fast approval process — many patients approved within 24 hours
- ✓Licensed providers handle all prescribing decisions
Direct Meds
- ✓GLP-1 medications with transparent, upfront pricing
- ✓Fast approval process — many patients approved within 24 hours
- ✓Licensed providers handle all prescribing decisions
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Simple start: $149/mo with expert support
Wellorithm
- ✓Weight management made straightforward with expert guidance
- ✓Licensed providers prescribe GLP-1 medications as appropriate
- ✓Simple enrollment and fast approval process
Wellorithm
- ✓Weight management made straightforward with expert guidance
- ✓Licensed providers prescribe GLP-1 medications as appropriate
- ✓Simple enrollment and fast approval process
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Hassle-free refills from just $139/mo
Refills
- ✓Convenient refill service for weight management medications
- ✓Licensed providers manage prescriptions and ongoing care
- ✓Designed for easy, hassle-free medication continuity
Refills
- ✓Convenient refill service for weight management medications
- ✓Licensed providers manage prescriptions and ongoing care
- ✓Designed for easy, hassle-free medication continuity
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Provider offers a money-back guarantee — see terms
Fella Health
- ✓Provider offers a 6-month money-back guarantee — terms and conditions apply
- ✓Free personalized health coaching with bi-weekly video sessions
- ✓Free lab work included (in-clinic or at-home kits)
Fella Health
- ✓Provider offers a 6-month money-back guarantee — terms and conditions apply
- ✓Free personalized health coaching with bi-weekly video sessions
- ✓Free lab work included (in-clinic or at-home kits)
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Plans from $119/mo — most affordable GLP-1 option
G-Plans
- ✓Structured GLP-1 weight management plans
- ✓Licensed providers guide your treatment from start to finish
- ✓Clear, plan-based approach to weight management
G-Plans
- ✓Structured GLP-1 weight management plans
- ✓Licensed providers guide your treatment from start to finish
- ✓Clear, plan-based approach to weight management
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Budget-friendly at just $99/mo — lowest entry price
TeleHealth Med
- ✓Online weight management consultations with licensed providers
- ✓Affordable GLP-1 medication delivery programs
- ✓Simple platform designed for easy enrollment
TeleHealth Med
- ✓Online weight management consultations with licensed providers
- ✓Affordable GLP-1 medication delivery programs
- ✓Simple platform designed for easy enrollment
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Ro
- ✓Multiple medication options including branded GLP-1s
- ✓Insurance eligibility checker built into onboarding
- ✓Body Program combines GLP-1s with metabolic health coaching
Why Ro Is Our #1 Pick
- ✓Multiple medication options including branded GLP-1s
- ✓Insurance eligibility checker built into onboarding
- ✓Body Program combines GLP-1s with metabolic health coaching
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Medical Disclaimer
The content on this website is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The providers listed on this page offer compounded GLP-1 receptor agonist medications, which are not FDA-approved. Compounded medications are prepared by licensed pharmacies but have not undergone the same rigorous FDA review process as branded medications. Clinical trial results cited on this page (STEP 1, SURMOUNT-1) refer to branded, FDA-approved medications (Wegovy, Zepbound) and may not be representative of outcomes with compounded formulations. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
How GLP-1 Medications Support Weight Loss
Mechanism of Action
GLP-1 receptor agonists work by mimicking the naturally occurring hormone GLP-1 (glucagon-like peptide-1), which plays a key role in appetite regulation and blood sugar control.
- •Appetite suppression: Signals the brain to reduce hunger, helping patients eat less without feeling deprived
- •Delayed gastric emptying: Slows stomach emptying, increasing the feeling of fullness after meals
- •Blood sugar regulation: Improves insulin sensitivity and glucose metabolism, supporting overall metabolic health
Clinical Study Results
Note: The following results are from clinical trials of branded, FDA-approved medications. Individual results may vary. Compounded medications have not undergone the same clinical trials.
STEP 1 Trial — Semaglutide (Wegovy)
- ✓Average weight loss: 14.9% of body weight
- ✓Duration: 68 weeks
- ✓Published in: New England Journal of Medicine
SURMOUNT-1 Trial — Tirzepatide (Zepbound)
- ✓Average weight loss: up to 22.5% of body weight
- ✓Duration: 72 weeks
- ✓Published in: New England Journal of Medicine
Tirzepatide vs Semaglutide
| Factor | Semaglutide | Tirzepatide |
|---|---|---|
| Drug Class | GLP-1 agonist | Dual GIP/GLP-1 agonist |
| Branded Name (Weight Loss) | Wegovy | Zepbound |
| Avg. Weight Loss (Trials) | ~14.9% | ~22.5% |
| Administration | Weekly injection | Weekly injection |
| FDA-Approved | Yes (Wegovy) | Yes (Zepbound) |
5 Things to Look for in a GLP-1 Provider
- 1Clinical Oversight: Look for providers staffed by board-certified physicians or obesity medicine specialists — not just nurse practitioners.
- 2Transparent Pricing: The provider should clearly list first-month, ongoing, and any additional fees. Be wary of hidden costs for lab work or shipping.
- 3Medication Quality: Compounded medications should come from 503B-registered outsourcing facilities. Ask about their pharmacy partnerships.
- 4Ongoing Monitoring: Quality providers include regular check-ins, dose adjustments, and metabolic tracking — not just an initial prescription.
- 5Patient Support: Look for programs that include nutritional guidance, behavioral coaching, or community support alongside medication.
How Telehealth GLP-1 Treatment Works
Online Intake
Complete a health questionnaire and medical history form. Upload any relevant lab work or records.
Provider Review
A licensed physician reviews your profile, conducts a virtual consultation, and determines eligibility.
Medication Delivery
Your prescribed GLP-1 medication is shipped directly to your door in temperature-controlled packaging.
Our Top 3 Choices
Ro
- ✓Multiple medication options including branded GLP-1s
- ✓Insurance eligibility checker built into onboarding
- ✓Body Program combines GLP-1s with metabolic health coaching
Why Ro Is Our #1 Pick
- ✓Multiple medication options including branded GLP-1s
- ✓Insurance eligibility checker built into onboarding
- ✓Body Program combines GLP-1s with metabolic health coaching
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
MEDVi
- ✓GLP-1 injections prescribed and shipped direct to your door
- ✓Compounded semaglutide and tirzepatide available
- ✓Licensed physicians manage your treatment plan
MEDVi
- ✓GLP-1 injections prescribed and shipped direct to your door
- ✓Compounded semaglutide and tirzepatide available
- ✓Licensed physicians manage your treatment plan
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.
Spring Deal: Your first month only $149 + free shipping
FuturHealth
- ✓Branded Wegovy access through licensed providers
- ✓Insurance support to help offset medication costs
- ✓Compounded semaglutide also available alongside branded options
FuturHealth
- ✓Branded Wegovy access through licensed providers
- ✓Insurance support to help offset medication costs
- ✓Compounded semaglutide also available alongside branded options
Compounded medications are not FDA-approved. They are prepared by state-licensed compounding pharmacies.